Set in the 1960s, Billy Covington (Robert Downey Jr.) is a big-city chopper pilot who reports traffic conditions for a radio station but ends up losing his license due to a traffic incident on the freeway. Longing to do some real flying, Billy is recruited by the government for a secret and safe (he thinks) civilian airline in Laos. Knowing that by agreeing to do it he'll get his license back, he signs up. Upon arrival in Laos, he soon befriends ace pilot Gene Ryack (Mel Gibson) and realises that Air America isn't quite what it seems, instead of transporting civilians, it's food, money, ammunition and napalm that are the real cargo and the pilots are risking their lives daily.